[Effect of polysaccharides on biological activity of human lactoferrin].

The influence of neutral and ionic polysaccharides on the antioxidant (AOA) and detoxifying activities of lactoferrin (LF) and the duration of its circulation in the body was studied. In addition to natural polymers, we studied artificial chitosan derivatives with different functional groups. On the basis ofAOA test, five polysaccharides were selected.

[Sulfated polysaccharides and their anticoagulant activity (review)].

Published data on the sulfated polysaccharides of various origins that display an anticoagulant activity are summarized and analyzed. The methods used for producing semisynthetic derivatives are considered. A key role of the polysaccharide structure in the mechanisms of specific interaction with various blood plasma proteinases is discussed.

[Effects of intravenous injection of sulphated galactomannan on anticoagulant activity of rat plasma].

We studied anticoagulant activity in vitro and in vivo of sulfate depolymerisation galactomannan guar with the following characteristics: Man:Gal 1.64, molecular mass 127 kDa, sulfation degree 1.46.

[Anticoagulant activity of low-molecular-weight sulfated derivatives of galactomannan from Cyamopsis tetragonoloba (L.) seeds].

Galactomannan from seeds of Cyamopsis tetragonoloba (L.) Taub. (guar) was depolymerized using immobilized enzymatic preparation celloviridin.

[Depolymerisation of legume seed galactomannans by Celloviridin G20x].

The depolymerisation of legume seed Galactomannans by commercial preparation "Celloviridin G20x" to produce fragments of macromolecules with unchanged monomer ratio was studied. The hydrolysis of four galactomannans in whole range of monomer ratio for this phytopolysaccharide group 1.1-5.