[Subcellular distribution of adenosine system enzymes in the hypothalamus and hippocampus of the rat brain].

The subcellular distribution of 5'-nucleotidase and adenosine deaminase in rat brain hypothalamus and hippocampus was studied. In the hippocampus the 5'-nucleotidase activity was shown to be much higher than in the hypothalamus, while the adenosine deaminase activity, contrariwise, is nearly two times as high as that in the hypothalamus. During the analysis of subcellular distribution 5'-nucleotidase and adenosine deaminase were detected in all fractions under study, i.

[Effects of desoxycorticosterone on 5-nucleotidase and adenosine deaminase activity in the hypothalamus and hippocampus of the rat brain].

Influence of single (enzyme activities was determined 5h after the preparation) and multiple (for 7 days) DOCA administration on 5'-nucleotidase (EC 3.1.3.

[The effect of hydrocortisone on the activity of 5'-nucleotidase and adenosine deaminase in the hypothalamus and hippocampus of the rat brain].

The effect of single (1.4 and 24 h) and long-term (7 days) hydrocortisone intramuscular administration (5 mg/100 g of body mass) on 5'-nucleotidase and adenosine deaminase activities in homogenate and subcellular fractions of the rat brain hypothalamus and hippocampus has been studied. Enzymatic activity of adenosine metabolism in hypothalamus and hippocampus has been shown to undergo changes with the duration of hydrocortisone administration.

[The effect of splenic humoral factors on corticosteroid metabolism and the cAMP content in the liver of rats with experimental toxic hepatitis].

Corticosteroid metabolism in the liver and the level of c-AMP in the liver and spleen of rats with experimental toxic hepatitis were investigated after splenin administration. Hydrocortisone metabolites were isolated by a method of two-dimensional thin-layer chromatography. It was shown that their production and the level of c-AMP in the liver and spleen after simulation of experimental hepatitis were considerably reduced.