Publications by authors named "N M Karpova"
Article Synopsis
- Hypertensive disorders of pregnancy (HDP) pose significant risks, particularly concerning chronic hypertension (CHTN) and preeclampsia (PE), which have been previously linked to the ZNF831 gene's rs259983 variant.
- A case-control study was conducted to explore the relationship between this genetic marker and HDP in women with Gestational Diabetes Mellitus (GDM), but no connection was found between PE and rs259983.
- However, further analysis revealed that the rs259983 variant is associated specifically with PE superimposed on CHTN (SIPE), indicating that women with the CC genotype have a 5.05 times higher risk of developing SIPE when they also have GDM.
[The relationship between the development of post-stroke cognitive impairment and changes in the coagulation component of hemostasis].
Zh Nevrol Psikhiatr Im S S Korsakova
March 2024
Objective: To evaluate the relationship between the severity of post-stroke cognitive impairment (PSCI) and coagulation parameters assessed using the dynamic thrombophotometry.
Material And Methods: Thirty-five patients with hemispheric ischemic stroke (IS) with moderate neurological deficit at admission were included. All patients underwent a comprehensive clinical and instrumental assessment according to the current guidelines.
The purpose of this prospective pilot study was to evaluate the feasibility and effects of cognitive-motor intervention on the cognitive and motor abilities of pediatric survivors of posterior fossa tumors. The study involved patients aged 7 to 18 years with cognitive deficits who had completed primary treatment for posterior fossa tumors. 25 participants (M=11.
View Article and Find Full Text PDFHemostasis system in patients with schizophrenia and schizophrenia spectrum disorders was examined using "Fibrinodynamics" technology that allows evaluating the overal coagulation, fibrinolysis, and hemostasis potentials. All indices, except for the parameter characterizing the hemostasis balance, were statistically higher (p<0.0001) in patients than in healthy volunteers (control).
View Article and Find Full Text PDFBackground: The effects of the selective serotonin reuptake inhibitors (SSRIs), the first-line antidepressant treatment, have been proposed to be affected, at least in part, by the living environment. Since the quality of the environment depends not only on its objective features, but also on the subjective experience, we hypothesized that the latter plays a key role in determining SSRI treatment outcome.
Methods: We chronically administered the SSRI fluoxetine to two groups of adult CD-1 male mice that reportedly show distinct subjective experiences of the environment measured as consistent and significantly different responses to the same emotional and social stimuli.