Comparing MRI volume measurement techniques for pituitary macroadenoma: Investigating volume reduction and its relationship with biochemical control.

Pituitary adenomas are one of the most common types of primary intracranial tumors. Measuring pituitary adenoma volume is fundamental for effective management. This study aimed to assess the reliability of the ellipsoid method in comparison with the perimeter method for measuring pituitary macroadenoma volume.

Evaluating Stacked Methylation Markers for Blood-Based Multicancer Detection.

The ability to detect several types of cancer using a non-invasive, blood-based test holds the potential to revolutionize oncology screening. We mined tumor methylation array data from the Cancer Genome Atlas (TCGA) covering 14 cancer types and identified two novel, broadly-occurring methylation markers at and . To evaluate their performance as a generalized blood-based screening approach, along with our previously reported methylation biomarker, , we rigorously assessed each marker individually or combined.

Field and Experimental Investigations on the Effect of Reservoir Drill-In Fluids on Penetration Rate and Drilling Cost in Horizontal Wells.

In this study, the reservoir drill-in fluid (RDF) was modified and optimized to improve the rheological properties and reduce the filtration properties of the drilling fluid used for drilling the oil-bearing zone horizontally. In polymer science, degradation generally refers to a complex process, by which a polymeric material exposed to the environment and workload loses its original properties. Degradation is usually an unwanted process.

Inhibition of sPLA enzyme activity by cell-permeable antioxidant EUK-8 and downregulation of p38, Akt, and p65 signals induced by sPLA in inflammatory mouse paw edema model.

The arachidonic acid (AA) metabolic pathway, plays a vital role in the production of eicosanoids by the action of pro-inflammatory secretory phospholipase A (PLA ). Release of eicosanoids is known to be involved in many inflammatory diseases. Identification of the inhibitory molecules of this AA pathway enzyme along with the regulation of intracellular signaling cascades may be a finer choice to develop as a powerful anti-inflammatory drug.

Syringol isolated from Eleusine coracana (L.) Gaertn bran suppresses inflammatory response through the down-regulation of cPLA, COX-2, IκBα, p38 and MPO signaling in sPLA induced mice paw oedema.

Eleusine coracana (L.) Gaertn (E. coracana) is one of the highest consuming food crops in Asia and Africa.