Zh Mikrobiol Epidemiol Immunobiol
March 2016
Aim: Study of the role of innate immunity factors, namely, expression of TLR2 and HBD-2 genes, as well as TNF-α arid TGF-β in pathogenesis of periodontium tissue inflammation.
Materials And Methods: 59 individuals with periodontitis illnesses were included into the study; 15 healthy donors represented the comparison group. Study of the TLR2 and HBD-2 gene expression levels was carried out by rRT-PCR, cytokine production evaluation--by EIA.