"How are you?" Estimation of anxiety, sleep quality, and mood using computational voice analysis.

We developed a method of estimating impactors of cognitive function (ICF) - such as anxiety, sleep quality, and mood - using computational voice analysis. Clinically validated questionnaires (VQs) were used to score anxiety, sleep and mood while salient voice features were extracted to train regression models with deep neural networks. Experiments with 203 subjects showed promising results with significant concordance correlation coefficients (CCC) between actual VQ scores and the predicted scores (0.

Molecular Support for Heterogonesis Resulting in Sesquizygotic Twinning.

Sesquizygotic multiple pregnancy is an exceptional intermediate between monozygotic and dizygotic twinning. We report a monochorionic twin pregnancy with fetal sex discordance. Genotyping of amniotic fluid from each sac showed that the twins were maternally identical but chimerically shared 78% of their paternal genome, which makes them genetically in between monozygotic and dizygotic; they are sesquizygotic.

A unique F MRI agent for the tracking of non phagocytic cells in vivo.

There is currently intense interest in new methods for understanding the fate of therapeutically-relevant cells, such as mesenchymal stem cells (MSCs). The absence of a confounding background signal and consequent unequivocal assignment makes 19F MRI one of the most attractive modalities for the tracking of injected cells in vivo. We describe here the synthesis of novel partly-fluorinated polymeric nanoparticles with small size and high fluorine content as MRI agents.

Meso-Endothelial Bipotent Progenitors from Human Placenta Display Distinct Molecular and Cellular Identity.

The existence of bipotential precursors for both mesenchymal and endothelial stem/progenitor cells in human postnatal life is debated. Here, we hypothesized that such progenitors are present within the human term placenta. From a heterogeneous placental single-cell suspension, a directly flow-sorted CD45CD34CD144CD31Lo population uniquely differentiated into both endothelial and mesenchymal colonies in limiting dilution culture assays.