[Morphological characteristics of chorion in spontaneous abortions of chromosomic etiology].

Morphological investigation of spontaneous abortions (SA) with normal and abnormal karyotype (220 specimens of the first trimester SA) was carried out. It included a histological pattern, apoptosis and proliferative activity. Estimation of apoptotic index (AI) was carried out in 7 cases of SA with normal karyotype and 7 cases of SA with pathological karyotype using the ApopTag Peroxidase Kits (Biotech, USA).

[Cytogenetic screening of workers of rubber manufacturing industry].

Cytogenetic analysis of lymphocytes was performed in 36 preparatory workers engaged into rubber shoes and general mechanical rubber goods production. Preparatory workers and management staff had the same chromosomal aberrations frequency. Although chromosomal aberrations frequency in employees of the enterprise appeared to be twice as much as that for general population, which proves hazardous factors of rubber production to afflict genofond of employees.

[Use of the calculation of the micronuclei in human cells in the detection of cytogenetic injuries by environmental factors].

The review is concerned with an analysis of the data reported in this country and abroad on the use of micronuclei calculation for revealing cytogenetic injuries by environmental factors. It has been shown that the micronucleus test possesses a rather high sensitivity, provides information and affords an objective judgement about the action of mutagenic environmental factors on man.