Publications by authors named "N M Cowen"

Food fraud is an ever-present threat that regulators, food business operators (FBOs), and consumers need to be aware of, prevent where possible, and address by developing mitigation strategies to detect and reduce its negative consequences. While extant literature focuses on food fraud detection, there is less attention given to prevention strategies, a knowledge gap this review seeks to address. The aim of this review was to consider food-related fraud prevention initiatives, understand what has worked well, and develop a series of recommendations on preventing food fraud, both policy related and for future research.

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Article Synopsis
  • Prader-Willi syndrome (PWS) is a rare genetic disorder linked to the absence of certain genes on chromosome 15, leading to symptoms like low muscle tone, cognitive issues, and a constant urge to eat, which can cause severe obesity if not managed.
  • The study assessed the long-term effectiveness of Diazoxide choline extended-release (DCCR) tablets on managing hyperphagia and other behavioral issues in PWS patients through comparisons between a treatment cohort and a natural history study cohort.
  • Results showed that those treated with DCCR exhibited significant reductions in hyperphagia scores and improvements in behavioral assessments over 26 and 52 weeks, with findings remaining consistent even under worst-case data scenarios. *
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Objective: This study assessed the effect of 1-year administration of diazoxide choline extended-release tablet (DCCR) on hyperphagia and other complications of Prader-Willi syndrome (PWS).

Methods: The authors studied 125 participants with PWS, age ≥ 4 years, who were enrolled in the DESTINY PWS Phase 3 study and who received DCCR for up to 52 weeks in DESTINY PWS and/or its open-label extension. The primary efficacy endpoint was Hyperphagia Questionnaire for Clinical Trials (HQ-CT) score.

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Background: Health professionals are increasingly being called to address the social determinants of health (SDOH) and, to do so effectively, often requires an integrated approach to care. As a result, accreditation standards across multiple professions have emphasised the importance of interprofessional education (IPE).

Approach: This paper describes large-scale, community-engaged learning that is required annually of students from nursing, pharmacy, public health, and social work.

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Novel externalities are social activities for which the emerging cost (or benefit) of the spillover is unknown and must be discovered. Negative novel externalities have regained international salience following the COVID-19 pandemic. Such cases frequently are invoked as evidence of the limits of liberal political economy for dealing with public emergencies.

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