Publications by authors named "N M Bom"
Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas.
Genet Mol Biol
January 2024
Article Synopsis
- * In a study examining Brazilian patients with lung adenocarcinoma, sarcoma, and uterine leiomyoma, the minor allele (C) of this variant was found in only 1.02% of LUAD cases, while none were detected in SARC or ULM samples.
- * Although the prevalence of rs78378222 is low in the specific tumors studied, the findings suggest that further analysis in Brazilian regions is not necessary, but molecular testing for this variant should still be considered in other populations.
With Switzerland's population ageing, promoting healthy ageing remains a public health issue. This represents a challenge for the healthcare system, which is still mainly focused on curative or palliative care. It has been clearly established that it is possible to maintain the functional capacity of older people by taking early action on health-related behaviors.
View Article and Find Full Text PDFBackground: At border sites, and in internal organs, tissue resident memory T cells (T contribute to the immune barrier against pathogens like viruses, bacteria, fungi, and cancer. However, information on the presence and function of these cells in the human kidney is scant. In order to better understand the T cell-mediated immunological defense in this organ, we aimed to determine phenotypic and functional aspects of CD8 and CD4 T cells present in healthy and allograft kidney tissue.
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