Publications by authors named "N M A van der Hoeven"
Age-related structural remodelling of the coronary circulation.
Catheter Cardiovasc Interv
November 2024
Article Synopsis
- - The study explores how aging affects the structure and function of coronary microvessels in patients with stable angina, without significant blockage in their main coronary arteries.
- - Researchers analyzed data from 165 vessels, finding that older patients (ages 67-77) exhibited lower hyperemic flow velocity, diminished diastolic microvascular conductance (DMVC), and reduced backward expansion wave (BEW) intensity compared to younger groups.
- - Results indicate that aging leads to structural changes in coronary microcirculation, increasing the prevalence of coronary microvascular dysfunction (CMD) among older individuals, which is crucial for understanding heart issues in elderly patients.
Article Synopsis
- In out-of-hospital cardiac arrest (OHCA) cases without ST-elevation, researchers investigated the usefulness of troponin-T (cTnT) levels in predicting the risk of acute coronary syndrome and patient survival.
- The study analyzed data from 352 patients, revealing that higher cTnT values were independent predictors for 90-day mortality and the presence of acute unstable lesions and thrombotic occlusions.
- However, cTnT levels did not show a significant correlation with left ventricular function, highlighting its role primarily in assessing mortality risk and acute coronary issues in these patients.
Background: The aim of this study was to determine attitude of Dutch midwifes, gynecologists and general practitioners (GPs) towards involvement in antenatal cervical cancer screening (CCS) in the Netherlands.
Methods: In 2021, Dutch midwives, gynecologists, and GPs were offered a single digital questionnaire assessing perceived feasibility, benefits, and harms of antenatal CCS.
Results: A total of 6943 Questionnaires were send and response rate was 18% (N = 1260).
Background: Microvascular obstruction (MVO) measured by cardiac magnetic resonance (CMR) after ST-segment elevation myocardial infarction (STEMI) has important prognostic implications. While invasive index of microvascular resistance (IMR) have been shown to predict the occurrence and extent of MVO, the role of the angiography-based microvascular resistance (Angio-IMR) for this purpose remains unknown. The present study aims to perform a head-to-head comparison of wire-based and angiography-derived microcirculatory resistance (IMR and Angio-IMR, respectively) for the detection of MVO.
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- The study explored how the timing of treatment (symptom-to-reperfusion time) affects heart damage in patients with ST-segment elevation myocardial infarction (STEMI) after undergoing primary percutaneous coronary intervention (PPCI).
- Researchers divided 108 STEMI patients into two groups based on their reperfusion time and found that shorter reperfusion times were linked to less heart damage (smaller infarct size) and better heart function measured by cardiovascular magnetic resonance (CMR).
- The findings suggest that a quicker treatment response correlates with better recovery of heart muscle function, particularly in circumferential and radial strain measurements, which are important for assessing heart health after an infarction.