Publications by authors named "N Lynn Ferguson"
Background: Survivorship after coronavirus disease 2019 (COVID-19) critical illness may be associated with important long-term sequelae, but little is known regarding mental health outcomes.
Research Question: What is the association between COVID-19 critical illness and new post-discharge mental health diagnoses.
Study Design: AND METHODS: We conducted a population-based cohort study in Ontario, Canada (January 1, 2020-March 31, 2022).
Timing of Extubation in Adult Patients with Acute Brain Injury.
Am J Respir Crit Care Med
November 2024
Article Synopsis
- The study investigates whether immediate extubation after a successful breathing trial benefits adults with acute brain injuries.
- It analyzed data from 1,406 patients in Toronto, focusing on those who were mechanically ventilated and had successful breathing trials.
- The findings suggest that prompt extubation is linked to an increase in ventilator-free days, indicating that it may be beneficial for recovery in these patients.
Background: Mathematical models and advanced analytics play an important role in policy decision making and mobilizing action. The Imperial College Coronavirus Disease 2019 (COVID-19) Response Team (ICCRT) provided continuous, timely and robust epidemiological analyses to inform the policy responses of governments and public health agencies around the world. This study aims to quantify the policy impact of ICCRT outputs, and understand which evidence was considered policy-relevant during the COVID-19 pandemic.
View Article and Find Full Text PDFAssessing yellow fever outbreak potential and implications for vaccine strategy.
PLOS Glob Public Health
November 2024
Yellow fever (YF), a vector-borne viral hemorrhagic fever, is endemic in tropical regions of Africa and South America, with large vaccination programmes being used for control. However, significant outbreaks have occurred in recent years. Data on infection rates and seroprevalence is often sparse, requiring robust mathematical models to estimate the burden of yellow fever.
View Article and Find Full Text PDFObjectives: We sought to evaluate whether different subgroups of adults with acute respiratory distress syndrome (ARDS) respond differently to high-frequency oscillatory ventilation (HFOV).
Design: The Oscillation for ARDS Treated Early (OSCILLATE) trial was a randomized controlled trial of HFOV vs. conventional ventilation that found an increased risk of in-hospital mortality (primary outcome) with HFOV.