Publications by authors named "N Lieberman"
Article Synopsis
- Leishmaniasis is a rare but underreported disease in the U.S., primarily affecting travelers and migrants, with an annual incidence of only a few dozen cases, making true rates difficult to ascertain.
- From September 2021 to August 2022, a national reference laboratory tested 218 specimens, identifying 50.5% as positive, mostly linked to subgenus species causing cutaneous or mucocutaneous diseases.
- The study underscores the need for improved molecular testing and reveals a higher-than-reported incidence of mucosal leishmaniasis and greater genetic diversity within species found in the Americas.
The recently discovered methodologies to cultivate and genetically manipulate Treponema pallidum subsp. pallidum (T. pallidum) have significantly helped syphilis research, allowing the in vitro evaluation of antibiotic efficacy, performance of controlled studies to assess differential treponemal gene expression, and generation of loss-of-function mutants to evaluate the contribution of specific genetic loci to T.
View Article and Find Full Text PDFDoxycycline post-exposure prophylaxis (doxy-PEP) could significantly reduce syphilis incidence. However, the increase in intermittent doxycycline usage might select resistant Treponema pallidum (T. pallidum) strains.
View Article and Find Full Text PDFBackground: Histologic and serologic studies suggest the induction of local and systemic Treponema pallidum-specific CD4+ T-cell responses to T. pallidum infection. We hypothesized that T.
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