Background: Cutaneous bullous mastocytosis (CBM) is a rare disease characterised by erythroderma, bullae formation on trunk, scalp and extremities which evolve to erosions.
Objective: To describe a rare variant of cutaneous mastocytosis and treatment options.
Animal: A 7-month-old Yorkshire terrier puppy with erythroderma and bullae formation.
Ichthyoses are hereditary cornification disorders that manifest with abnormal differentiation and desquamation of keratinocytes in a form of generalized dry and scaly skin. In golden retriever dogs, autosomal recessive congenital ichthyosis (ARCI) has been associated with mutations in the gene. In human medicine, isotretinoin is frequently used to treat ARCIs.
View Article and Find Full Text PDFBackground: Currently, there is insufficient evidence to confirm oral diphenhydramine (DPH) efficacy to prevent mast cell degranulation and histamine release in dogs.
Hypothesis/objective: To determine and compare the effects oral of DPH and cetirizine on the immediate- and late-phase cutaneous allergic reactions in healthy dogs.
Animals: Twelve healthy laboratory beagle dogs.
Background: Polihexanide (polyhexamethylene biguanide) is an antiseptic substance that plays a prominent role in the treatment of critically colonized or infected acute and chronic wounds in humans.
Hypothesis/objectives: The aim of this study was to assess the in vitro antimicrobial efficacy of polihexanide against canine isolates of Staphylococcus pseudintermedius, Pseudomonas aeruginosa and Malassezia pachydermatis and compare it with 4.5% chlorhexidine digluconate for two different contact times.