Publications by authors named "N Le Berre"
Article Synopsis
- - Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent among obese individuals and shows differences between sexes. A study sought to create a noninvasive blood test using mid-infrared (MIR) metabolic fingerprinting to diagnose metabolic dysfunction-associated steatohepatitis (MASH) in those with severe obesity.
- - The study involved 382 patients undergoing bariatric surgery, with liver biopsies assessed to establish a scoring algorithm based on MIR spectroscopy. In women, MASH was diagnosed in 14.3% of cases, showing high sensitivity (86%) and specificity (81%) for correctly identifying the condition.
- - For men, the test's performance was notably less effective, with a MASH diagnosis
In some situations, there is a need for rapid mutation tests for guiding clinical decisions and starting targeted therapies with minimal delays. In this study we evaluated the turnaround time before and after the implementation of a fully automated multiplex assay for KRAS and NRAS/BRAF mutation tests (Idylla™ platform, Biocartis) in metastatic colorectal cancer. The objective of this project was to compare the turnaround times in 2017-2018 with the fully automated multiplex assay to the 2016 results with previous methods.
View Article and Find Full Text PDFAntibiotic therapy in case of positive cultures of kidney transplant preservation fluid: a nationwide survey of prescribing practices.
Eur J Clin Microbiol Infect Dis
May 2020
Our survey aimed to describe current prescribing practices for perioperative antibiotic prophylaxis in French kidney transplant centers. We conducted a nationwide cross-sectional clinical vignette-based survey that we sent via email to hospital practitioners involved in perioperative management of kidney transplant patients (KTR). Nearly half of practitioners contacted (182/427, 42.
View Article and Find Full Text PDFObjectives: Kidney transplant recipients are at high-risk for donor-derived infections in the early post-transplant period. Transplant preservation fluid (PF) samples are collected for microbiological analysis. In case of positive PF cultures, the risk for the recipient is unknown and there is no consensus for prescribing prophylactic antibiotics.
View Article and Find Full Text PDFPost-infectious glomerulonephritis has become exceptional in France because streptococcus infections are well-treated. When they appear, clinical and biological symptoms are mostly typical and associate acute nephritic syndrome, acute renal failure, proteinuria, hematuria and low complement. We are reporting the first French case of acute post-infectious glomerulonephritis related to Streptococcus equi subsp.
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