Publications by authors named "N Laufer"
Article Synopsis
- The study aimed to analyze the immune characteristics and viral makeup of young adults in Argentina who acquired HIV at birth (p-YA), comparing them to young adults with HIV acquired through other means.
- Researchers conducted a detailed examination of immune cell types and their functions using techniques like flow cytometry and ELISA, involving 18 p-YA and various control groups.
- Key findings revealed that p-YA had a unique immune profile with more naïve CD4 T-cells and lower signs of exhaustion, suggesting they face different challenges in managing the HIV virus compared to those who acquired it later in life.
The development of effective HIV cure strategies is crucial. However, most research in this area has been concentrated in high-income countries, underscoring the need to expand efforts to regions like Latin America and the Caribbean (LAC), which face distinct biomedical, social, political, and economic challenges. Data on LAC's participation in HIV cure research, along with stakeholder perceptions, reveal that the work being done in the region is scarce, fragmented, scattered, and characterized by limited resources and infrastructure.
View Article and Find Full Text PDFMore than 62,000 individuals are currently on antiretroviral treatment within the public health system in Argentina. In 2019, more than 50% of people on ART received non-nucleoside reverse transcriptase inhibitors (NNRTIs). In this context, the second nationwide HIV-1 pretreatment drug resistance surveillance study was carried out between April and December 2019 to assess the prevalence of HIV-1 drug resistance in Argentina using the World Health Organization guidelines.
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