Publications by authors named "N Lapidus"
Article Synopsis
- A study analyzed lung cancer cases in France during the COVID-19 pandemic by comparing 2020-2021 data with pre-pandemic years (2013-2019), focusing on diagnosis and mortality rates.
- Findings revealed a 12% decrease in newly diagnosed lung cancer cases during the first wave of the pandemic, with a continued improvement in survival rates over time, even during the pandemic.
- The decrease in lung cancer incidences could be linked to undiagnosed patients who died due to COVID-19 or challenges in accessing healthcare, leading to excess mortality during this period.
Article Synopsis
- Human metapneumovirus (hMPV) is a major cause of respiratory infections, and this study focused on adult patients with hMPV-related lower respiratory tract infections to evaluate their clinical features and outcomes.
- A total of 208 patients were studied, with a median age of 74 years; most patients had coexisting health issues, and common symptoms included difficulty breathing and cough, while pneumonia was the most frequent diagnosis.
- The study found that 18% of patients had a complicated course requiring intensive care, with a notable increased risk in those with bacterial coinfections, suggesting the need for careful monitoring and potential early intervention in this population.
Atrial fibrillation (AF) is the most common heart rhythm disorder in clinical practice. It worsens the quality of life of patients, leads to an increase in the mortality rate because of its association with a high risk of thromboembolic complications. The current pandemic of a new coronavirus infection, which began in March 2020, was marked by an increase in cardiovascular diseases, including an increase in the number of patients with AF.
View Article and Find Full Text PDFThe individual results of SARS-CoV-2 serological tests measured after the first pandemic wave of 2020 cannot be directly interpreted as a probability of having been infected. Plus, these results are usually returned as a binary or ternary variable, relying on predefined cut-offs. We propose a Bayesian mixture model to estimate individual infection probabilities, based on 81,797 continuous anti-spike IgG tests from Euroimmun collected in France after the first wave.
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- Patients with COVID-19 requiring mechanical ventilation have a high risk of developing ventilator-associated pneumonia (VAP), particularly caused by Enterobacterales, with limited data on extended-spectrum beta-lactamase producing Enterobacterales (ESBL-E).
- In a study involving 591 patients with Enterobacterales related VAP, 19% developed ESBL-E infections, primarily from Enterobacter sp, K. pneumoniae, and E. coli, while a very small percentage experienced carbapenem-resistant Enterobacterales (CRE) infections.
- Key risk factors for ESBL-E related VAP included African origin, time between intubation and VAP development, the patient's oxygenation status, and prior exposure to trimethopr