Publications by authors named "N Lange"

Direct oral anticoagulant (DOAC) use has significantly increased because major medical organizations endorse their role for conditions in which anticoagulation is indicated. Owing to important pharmacokinetic properties, the use of apixaban and rivaroxaban requires careful consideration in at-risk populations such as those with kidney disease. Both apixaban and rivaroxaban undergo some degree of renal elimination, and thus total drug exposure is increased in patients with renal insufficiency and/or those undergoing renal replacement therapy (RRT).

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: The objectives of this study were (1) to systematically review the currently used definitions of incidental 2-deoxy-2-[F]fluoro-D-glucose positron emission tomography/computed tomography findings (IPFs) in the literature and (2) to propose an IPF definition. : A systematic search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The search was guided by the question "How is IPF defined?" and was performed in MEDLINE, Embase, and the Cochrane Library.

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Article Synopsis
  • Roux-en-Y gastric bypass (RYGB) surgery can cause post-bariatric hypoglycaemia (PBH) due to changes in glucose handling by the liver.
  • A study compared RYGB patients with PBH to healthy controls by tracking glucose and hormone levels after consuming glucose, using advanced imaging techniques.
  • Results showed that RYGB patients had distinct glucose and insulin responses, including a quicker rise and fall in glucose levels and lower sensitivity to insulin, but did not have impaired liver glucose uptake or output contributing to PBH.
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  • Visual impairment is a major public health issue for older adults in Poland, with a study focusing on the influence of socioeconomic factors and health status on this problem.
  • A total of 5,987 individuals aged 60 and older were analyzed, revealing that older age, lower education, and certain past occupations significantly increase the odds of visual impairment.
  • Interestingly, obesity was linked to a lower likelihood of visual impairment, suggesting complex relationships between health and socioeconomic status.
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Purpose: To report results following deltoid ligament reconstruction in a large series of patients.

Methods: For consecutive patients who had a medial ankle ligament stabilization 2010-2018 information from their medical files was registered, and they were invited for follow-up in 2021-2022. They answered questions about satisfaction with the treatment and current symptoms, and they completed the Foot and Ankle Measurement (FAAM) questionnaire.

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