Publications by authors named "N Lakmal Mudalige"
Background And Aim: In British Columbia, Canada, clinical guidelines for the treatment of opioid use disorders (OUD) were updated in 2017, during a period in which the potency and composition of the illicit drug supply changed rapidly. We aimed to describe changes in opioid agonist treatment (OAT) prescribing practices at the population level in a setting in which fentanyl and its analogs have become the primary illicit opioid of use.
Design, Setting And Participants: This was a population-based retrospective cohort study using three linked health administrative databases in British Columbia (BC), Canada.
Aims: The risk, characteristics, and outcome of out-of-hospital cardiac arrest (OHCA) in patients with congenital heart disease (CHD) remain scarcely investigated.
Methods And Results: An epidemiological registry-based study was conducted. Using time-dependent Cox regression models fitted with a nested case-control design, hazard ratios (HRs) with 95% confidence intervals of OHCA of presumed cardiac cause (2001-19) associated with simple, moderate, and severe CHD were calculated.
Article Synopsis
- The growth of large data sets from modern technology demands updated statistical models for effective analysis, which is particularly relevant for plant CT scanning to study tree branching and leaf canopies.
- The study presents a method to analyze tree branching structures by representing branches as 3D line segments classified in a hierarchical order, focusing on four key characteristics: position, orientation, length, and number of offspring.
- Through statistical modeling of CT scanned trees, it is found that the length of trunk branches significantly influences the overall structure and characteristics of the tree, highlighting its importance in understanding tree growth patterns.
Background: The UK Renal Registry is responsible for the national collection and reporting of data on all children receiving long-term kidney replacement therapy [KRT], including kidney transplantation.
Methods: All 13 UK pediatric nephrology centers contributed to providing individual patient data from the pediatric population incident to and prevalent to KRT as per the date 31 December 2018. Data for children aged 16-<18 years were presented separately as some were managed under adult care settings with different methods of data collection.