Due to the hierarchical organization of RNA structures and their pivotal roles in fulfilling RNA functions, the formation of RNA secondary structure critically influences many biological processes and has thus been a crucial research topic. This review sets out to explore the computational prediction of RNA secondary structure and its connections to RNA modifications, which have emerged as an active domain in recent years. We first examine the progression of RNA secondary structure prediction methodology, focusing on a set of representative works categorized into thermodynamic, comparative, machine learning, and hybrid approaches.
View Article and Find Full Text PDFWe report on the synthesis and characterization of an imine-type nickel complex produced the complexation of an generated 2-(iminomethyl)phenol ligand with Ni ion. The use of this complex as an electrocatalyst for H evolution in a DMF solution, with acetic acid as the proton source, was investigated in detail, employing both experimental analyses (electrochemical analysis, spectroscopy analysis) and theoretical analysis (plateau current analysis). The overpotential required for H evolution is about 590 mV with a faradaic efficiency of 49% after 3 hours bulk electrolysis, competing with the two-electron reduction of free-imine groups in the ligand.
View Article and Find Full Text PDFUterine leiomyoma, also referred to as fibroid or myoma, is a prevalent benign tumor that can present with a range of clinical manifestations. The symptoms, which vary based on the tumor's location, size, and number, include pain, constipation, urinary disturbances, and abnormal menstrual bleeding. Certain types of uterine leiomyomas, such as pedunculated subserosal myomas or large degenerating cystic myomas, may closely mimic ovarian tumors, leading to significant diagnostic and management challenges.
View Article and Find Full Text PDF(GF) is a red seaweed that is widely found in Southeast Asia and has gained attention for its potential bioactive compounds and versatile applications in food products. This study explored the potential of GF as a natural gelling agent in the development of sustainable strawberry-based drinking jelly. By utilizing GF at varying concentrations (0.
View Article and Find Full Text PDFIntroduction: White matter (WM) tract degeneration is a characteristic feature of progressive supranuclear palsy (PSP), with longitudinal changes observed in PSP-Richardson's syndrome (PSP-RS). Little, however, is known about the other PSP variants. We assessed cross-sectional and longitudinal WM degeneration across PSP variants using diffusion tractography.
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