[Parameters of NO synthase system of gastric mucosa in rats under stress conditions and inhibition of cyclooxygenase].

In experiments on rats with modeled water-restrained stress, the influence of nonsteroidal anti-inflammatory drugs of different genesis on morphological status of gastric mucosa and changes of NO-synthase system parameters have been studied Administration of nonselective cyclooxygenese inhibitor naproxen in the water-restrained stress model in rats potentiated the increase of severity of damage of gastric mucosa. At the same time, the activity of both inducible and constitutive isoforms ofNO-sythase decreased. The parameters of lipoperoxidation remained at the level observed during water-restrained stress.

[Monitoring the health status in workers of chemical plants].

A morbidity level of workers in chemical industry depends on labour conditions, anthropometric dates and harmful habits. As informative signs of health state are 2-6 indices of humoral and cellular immunity. The age, social state and life duration in this town are less informative for health state.

[Children's health status in ecologically unfavorable regions].

Comparison of the official and research data on congenital developmental defects frequency (CDDF) in children of Novomoskovsk showed their disagreement. The average CDDF in these children is not more than the Middle European level. Physical development of children is insufficient for their biological age in 25% of cases.

[The morphological characteristics of psoriatic nephropathy].

Three variants of psoriatic nephropathy are distinguished on the basis of light microscopical and immunohistochemical study of 23 cases/20 kidney biopsies and 3 autopsy cases/: glomerulonephritis, amyloidosis and minimal kidney alterations. Chronic glomerulonephritis is mainly of a mesangioproliferative type with fixation of IgA and C3 on the mesangium and basal membranes of glomerular capillaries. Psoriatic amyloidosis has morphologically, all the features of acquired amyloidosis/AA-amyloidosis/.