Publications by authors named "N L Guevara"

Introduction: Tuberculous otomastoiditis is a rare and serious infection that most often occurs in association with pulmonary involvement. It is easy to diagnose when the two pathologies are associated and isolated. We herein report the case of a patient initially hospitalized for Pseudomonas aeruginosa necrotising otitis externa (NOE), which delayed the diagnosis of tuberculous otomastoiditis.

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Purpose/background: Clozapine is the recommended drug for treatment-resistant schizophrenia. Drug response could be affected by numerous factors such as age, sex, body mass index, co-medication, consumption of xanthine-containing beverages, smoking, and genetic variants of the enzymes involved in clozapine metabolism (CYP1A2, CYP3A4, and, to a lesser extent, CYP2C19 and CYP2D6). This study evaluated genetic and nongenetic variables that may affect clozapine plasma concentrations in Uruguayan patients with schizophrenia.

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Article Synopsis
  • - The paper introduces a budget-friendly electronic system designed to estimate ground reaction forces (GRF) during walking by utilizing a master node and two slave nodes connected to insole sensors placed in participants' shoes.
  • - The system employs 14 piezo-resistive sensors in each insole to collect data, which is then transmitted to a PC via USB after the walking session is completed, allowing for easy data retrieval through Wi-Fi.
  • - Validation against force platforms shows promising accuracy in dynamic situations, and future improvements will leverage machine learning models to enhance estimation precision.
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Background: Latinos are more likely than non-Latino Whites to develop dementia and be prescribed antipsychotics for dementia-related behavioral symptoms. Antipsychotics have significant risks yet are often overprescribed. Our understanding of how Latino caregivers of Latino older adults living with dementia perceive and address behavioral issues is limited, impeding our ability to address the root causes of antipsychotic overprescribing.

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