Publications by authors named "N Kuwahara"

Objectives: Cyclosporine A promotes gingival fibrosis by enhancing the proliferation of gingival fibroblasts, leading to gingival overgrowth. The population of gingival fibroblasts is regulated by cell cycle machinery, which balances cell growth and inhibition. Cells that detect DNA damage pause at the G1/S checkpoint to repair the damage instead of progressing to the S phase.

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  • The study examined the prevalence and characteristics of long COVID among patients hospitalized during the first three waves of COVID-19 in Japan.
  • Significant differences were found in patients' baseline health and outcomes, with those hospitalized in the first wave showing a higher incidence of long COVID symptoms, particularly dyspnoea.
  • The findings highlight the importance of ongoing monitoring and support for long COVID in patients, especially for those affected during the initial wave of the pandemic.
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Gingival overgrowth caused by cyclosporine A is due to increased fibroblast proliferation in gingival tissues. Cell cycle system balances proliferation and anti-proliferation of gingival fibroblasts and plays a role in the maintenance of its population in gingival tissues. When cells detect and respond to abnormalities (e.

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  • This study investigates how modified chair designs can create a safer and more effective environment for elderly individuals during unsupervised resistance training.
  • By involving 19 participants, the research measured the impact of these modified chairs on physical stability, comparing them to regular chairs used in chair-based exercise training.
  • Results showed that modified chairs significantly improved stability and user experience, but an automatic system is necessary to ensure proper exercise execution, achieving a high accuracy rate of 97.68% for movement recognition.
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  • * Even when applied after infection, it curbs lesion growth and sporulation, showcasing its versatility in both preventative and curative treatments.
  • * The chemical alters the fungus's physical characteristics, leading to abnormal structures and disrupting the normal localization of essential components for fungal growth, though it doesn't affect tubulin orientation.
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