Publications by authors named "N Kurosawa"

Article Synopsis
  • - KD-1 is a type of archaeon that thrives in extremely hot and acidic environments, first discovered in an Indonesian hot spring.
  • - The complete genome of KD-1 has been sequenced, revealing important genetic information about this organism.
  • - The genome contains genes linked to sulfur metabolism, suggesting that KD-1 plays a role in the sulfur cycle within its ecosystem.
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Article Synopsis
  • The study investigates the chemical constituents and virucidal activity of five species of Saxifraga, isolating 30 compounds in addition to tannins.
  • Two previously undescribed compounds were identified, including a benzoic acid derivative and a unique kaempferol glycoside, with specific stereochemistry changes observed in one of them when exposed to light.
  • Although the virucidal activities of the isolated compounds were weaker than those of the tannins from Saxifraga species, compounds with galloyl groups showed promising potential against various viruses, including influenza and coronaviruses.
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Members of the kingdom , previously known as DPANN archaea, are characterized by ultrasmall cell sizes and reduced genomes. They primarily thrive through ectosymbiotic interactions with specific hosts in diverse environments. Recent successful cultivations have emphasized the importance of adhesion to host cells for understanding the ecophysiology of .

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DPANN is a widespread and diverse group of archaea characterized by their small size, reduced genome, limited metabolic pathways, and symbiotic existence. Known DPANN species are predominantly obligate ectosymbionts that depend on their host for proliferation. The structural and molecular details of host recognition, host-DPANN intercellular communication, and host adaptation in response to DPANN attachment remain unknown.

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DPANN archaea are an enigmatic superphylum that are difficult to isolate and culture in the laboratory due to their specific culture conditions and apparent ectosymbiotic lifestyle. Here, we successfully isolated and cultivated a coculture system of a novel Nanobdellota archaeon YN1 and its host Sulfurisphaera ohwakuensis YN1HA. We characterized the coculture system by complementary methods, including metagenomics and metabolic pathway analysis, fluorescence microscopy, and high-resolution electron cryo-tomography (cryoET).

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