Publications by authors named "N Kurata"

Many older adults who are certified for long-term care services live or stay in long-term care facilities (LTCFs), where they receive medical and nursing care. These individuals often encounter medication-related problems, such as polypharmacy and complex medication regimens, including frequent administration schedules. Although considerable attention has been paid to polypharmacy in the context of optimizing medication use in older adults, little emphasis has been placed on simplifying these regimens.

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Purpose: To evaluate the impact of intravascular ultrasound (IVUS)-evaluated tissue morphology on recurrence following drug-coated balloon (DCB) angioplasty for the treatment of femoropopliteal in-stent restenosis (FP-ISR).

Methods: This study was a single-center, retrospective, observational study. Study subjects were 65 FP-ISR lesions (mean lesion length: 165 ± 88 mm, occlusive restenosis: 25%) in 53 patients (age: 76 ± 8, diabetes mellitus: 66%) who underwent DCB angioplasty and whose IVUS data of tissue morphology were available.

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Article Synopsis
  • Elderly patients often face feeding and swallowing issues, leading to the use of the simple suspension method where tablets are dissolved in warm water for tube administration without crushing.
  • A study using verapamil revealed that drug release was faster from crushed tablets than from the simple suspension or intact tablets, indicating significant differences in dissolution profiles.
  • While both crushing and simple suspension methods can safely help patients with dysphagia, they may also increase the risk of side effects, so it's advisable to avoid altering medications before giving them.
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