Publications by authors named "N Kurashvili"

Article Synopsis
  • The study assessed the ability of rheumatoid arthritis patients, who had no prior experience with self-injecting adalimumab, to self-administer a biosimilar called AVT02 using a custom autoinjector.
  • Over an 8-week active period, patients successfully self-injected AVT02 with a 100% success rate and no reported handling issues, followed by an additional 48-week phase to monitor long-term effects.
  • Results indicated that the autoinjector was effective and safe, showing no unexpected safety concerns or immunogenicity issues, confirming its suitability for RA patients.
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Halitosis--unpleasant smell from a mouth is widely spread pathology. Approximately one-fourth of world's population is suffering from this disease. Appearance of Halitosis is related not only with dental problems, but also with somatic disease.

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Immunological process develops as a result of the failure of mechanisms providing the state of conditional tolerance of maternal immune system in regard to antigens of feto-placental complex. Immune response is mainly directed towards maintenance of internal homeostasis of maternal organism in critical conditions, and as a result interruption of pregnancy takes occurs. Development of pregnancy leads to more expressed decrease of T-cellular indices, as well as of humoral immunity.

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Using clinical and experimental-psychological methods (a method of fixed orientation), the authors have studied 34 adolescents with continuous schizophrenia whose manifestation was attended by some exogenic factors (psychogenies, somatogenies, tox-infectious, and cranial traumas). The results obtained indicate some complications of psychopathological disturbances at the initial stage, manifesting in their marked acuteness, extension of the polymorphic spectrum and inclusion of heteronomous formations uncharacteristic of schizophrenia. A group of heteronomous manifestations should include sensorium disorders, pronounced emotional lability, general cerebral impairments, episodes of visual illusions and hallucinations, etc.

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