Publications by authors named "N Kundu"
Exosomes are extracellular vesicles within the nanosized range that play roles in intercellular communication and thus have certain biological activities. The secretory signaling communication mechanism is an efficient way of exchanging information between cells and has been investigated as nature's therapeutic drug carriers. This review will summarize the potential of exosomes as therapeutic tools and drug delivery vehicles for corneal pathologies.
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- Schizophrenia can impair thinking and motivation, and the study investigates the effects of daidzin (DZN) on mice to see if it improves cognitive functions like attention and memory.
- A series of behavioral tests, including marble burying and swimming tasks, were conducted on Swiss mice divided into groups receiving different doses of DZN and a standard drug called olanzapine (OLN).
- Results showed that DZN significantly improved attention and memory-related behaviors, particularly in combination with OLN, while in silico analysis revealed that DZN has strong interactions with serotonin and dopamine receptors, suggesting a potential mechanism for its effects.
Jellyfish are known for experiencing periodic blooms in population, which occur when their density increases suddenly. The present study assessed the level of heavy metals and proximate composition in the jellyfish Lobonemoides robustus collected from Cox's Bazar coast of Bangladesh. This is the first study conducted in Bangladesh.
View Article and Find Full Text PDFPurpose: To describe four cases of non-infectious hypertrophic pachymeningitis (HP)-associated with orbital inflammatory disease (OID). This study summarises the clinico-radiological features, outcomes, and management of HP-associated OID.
Methods: Retrospective case-series of patients with radiological evidence of HP and OID.
For the first time, the c-Myc G4 structure is reported to be stabilized by binding of the peptide (derived from the 2KRR domain of the nucleolin protein called the Nu peptide) in the loop region of the G-quadruplex structure by stacking interactions. CD results showed the formation of parallel G4 structure in the presence of 100 mM Na or 100 mM K with the appearance of two isodichroic points at 229 nm, 254 nm and 252 nm in the presence of 100 mM Na or 100 mM K, respectively. In addition, in UV thermal and CD melting studies, we observed drastic changes with an increase in the hyperchromicity at a DNA : peptide ratio of 1 : 50.
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