Hydrogen-bonding interactions in 5-fluorocytosine-urea (2/1), 5-fluorocytosine-5-fluorocytosinium 3,5-dinitrosalicylate-water (2/1/1) and 2-amino-4-chloro-6-methylpyrimidine-6-chloronicotinic acid (1/1).

Three new compounds, namely, 5-fluorocytosine-urea (2/1), 2CHFNO·CHNO, (I), 5-fluorocytosine-5-fluorocytosinium 3,5-dinitrosalicylate-water (2/1/1), 2CHFNO·CHFNO·CHNO·HO, (II), and 2-amino-4-chloro-6-methylpyrimidine-6-chloronicotinic acid (1/1), CHClNO·CHClN, (III), have been synthesized and characterized by single-crystal X-ray diffraction. In compound (I), 5-fluorocytosine (5FC) molecules A and B form two different homosynthons [R(8) ring motif], one formed via N-H..

Copper oxide nanoparticles fabricated by green chemistry using Tribulus terrestris seed natural extract-photocatalyst and green electrodes for energy storage device.

Nanobiotechnology is a unique class of multiphase and recently become a branch of contemporary science and a paradigm shift in material research. One of the two main problems facing the field of nanomaterial synthesis is the discovery of new natural resources for the biological production of metal nanoparticles and the absence of knowledge about the chemical composition of bio-source required for synthesis and the chemical process or mechanism behind the production of metal nanoparticles presents the second difficulty. We reported template-free green synthesized copper oxide nanoparticles using Tribulus terrestris seed natural extract without any isolation process.

Supramolecular interactions in some organic hydrated 2,4,6-triaminopyrimidinium carboxylate and sulfate salts.

Four salts, namely, 2,4,6-triaminopyrimidinium 6-chloronicotinate dihydrate, CHN·CHClNO·2HO, (I), 2,4,6-triaminopyrimidinediium pyridine-2,6-dicarboxylate dihydrate, CHN·CHNO·2HO, (II), 2,4,6-triaminopyrimidinediium sulfate monohydrate, CHN·SO·HO, (III), and 2,4,6-triaminopyrimidinium 3,5-dinitrobenzoate dihydrate, CHN·CHNO·2HO, (IV), were synthesized and characterized by X-ray diffraction techniques. Proton transfer from the corresponding acid to the pyrimidine base has occurred in all four crystal structures. Of the four salts, two [(I) and (IV)] exist as monoprotonated bases and two [(II) and (III)] exist as diprotonated bases.

Correction: The clinical spectrum and natural history of early-onset diseases due to DNA polymerase gamma mutations.

Since the online publication of the article, the authors have noted errors with Table 2; this has now been corrected in both the HTML and the PDF.

The clinical spectrum and natural history of early-onset diseases due to DNA polymerase gamma mutations.

PurposeMutations in POLG, the most common single-gene cause of inherited mitochondrial disease, are diagnostically challenging owing to clinical heterogeneity and overlap between syndromes. We aimed to improve the clinical recognition of POLG-related disorders in the pediatric population.MethodsWe performed a multinational, phenotype: genotype study using patients from three centers, two Norwegian and one from the United Kingdom.