Long-term study of isoprinosine in a case of subacute sclerosing panencephalitis.

A long-term study of isoprinosine, with temporary discontinuation of the treatment, in a 25-year-old man with subacute sclerosing panencephalitis is presented. Isoprinosine appears to have mainly an effect on the mental disturbances in stage I. EEG and CFS changes correlate well with the clinical course and the influence of isoprinosine.

Epilepsy in patients with cerebral infarcts.

Out of series of 240 patients, with proved cerebral infarcts at necropsy, 14 with a clinical history of epilepsy were selected. The possible etiology of seizures was analyzed by comparing the clinical and pathological data. It appeared from this series that epileptic spells, preceding for years the occurrence of a stroke, were due to other causes than to cerebrovascular insufficiency.