Publications by authors named "N Kourkoumelis"

Background: Diabetes mellitus (DM) and arthritis are prevalent conditions worldwide. The intricate relationship between these two conditions, especially in the context of various subtypes of arthritis, remains a topic of interest.

Objective: To investigate the relationship between diabetes and arthritis, with a focus on Rheumatoid Arthritis (RA), using data from the National Health and Nutrition Examination Survey (NHANES) and Mendelian Randomization (MR) analysis.

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Article Synopsis
  • An emerging multidrug-resistant fungal pathogen presents challenges in healthcare due to high misidentification and treatment resistance, highlighting a need for better identification methods.
  • The study utilized Raman spectroscopy on fungal cultures grown on modified Dixon's agar to differentiate among species, identifying key spectral markers that distinguish them into subgroups and using principal component analysis (PCA) for further differentiation.
  • The research also revealed a unique spectral signature for the modified agar, showcasing Raman spectroscopy's ability for real-time, non-destructive identification, despite the challenges posed by spectral similarity and variability among closely related fungi.
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Ethanol can be produced by many microorganisms that colonize a dead body. Ethanol's concentration depends on the congener higher alcohols, 1-propanol, isobutanol, 2-methyl-1-butanol, 3-methyl-1-butanol, and 1-butanol, as previous research has shown. This correlation is expressed by mathematical models which estimate the concentration of microbial ethanol.

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Non-melanoma skin cancer (NMSC) is the most prevalent cancer in humans, with a high global incidence. We present a prospective clinical feasibility study on the use of intraoperative flow cytometry (iFC) for the instant diagnosis of NMSC and its complete surgical clearance. Flow cytometry, a laser-based technique, quantifies cell features, which has applications in cancer research.

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Monitoring medical therapy remains a challenging task across all non-surgical skin cancer treatment modalities. In addition, confirmation of residual tumours after treatment is essential for the early detection of potential relapses. Optical coherence tomography (OCT), a non-invasive method for real-time cross-sectional imaging of living tissue, is a promising imaging approach for assessing relatively flat, near-surface skin lesions, such as those that occur in most basal cell carcinomas (BCCs), at the time of diagnosis.

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