Publications by authors named "N Koloski"
Background And Aim: In immunochemical fecal occult blood test (iFOBT) positive subjects, colonoscopy screening can detect colorectal cancers and advanced adenomas, yet most iFOBT-positive subjects find no relevant lower gastrointestinal lesions. Limited data are available on upper gastrointestinal (UGI) cancer risk in iFOBT-positive patients. This study investigated the incidence of UGI malignancies diagnosed within 3 years post-colonoscopy after a positive iFOBT.
View Article and Find Full Text PDFIntroduction: Little is known about the biogeography of the mucosa associated microbiome (MAM) in patients with inflammatory bowel disease (IBD) versus controls in different segments of the gastrointestinal tract, as well as the links between the MAM, gastrointestinal symptoms, and use of proton pump inhibitors (PPI).
Methods: We recruited 59 controls (without structural abnormalities and gastrointestinal symptoms), 44 patients with ulcerative colitis (UC) and 31 with Crohn's disease (CD). Biopsies from various segments of the upper and lower gastrointestinal tract were collected.
Article Synopsis
- The study explores Disorders of Gut Brain Interaction (DGBI), which are gastrointestinal issues linked with psychological conditions, highlighting that current diagnostic criteria (Rome IV) ignore psychological symptoms.
- Using data from the Rome Foundation Global Epidemiology Study, researchers applied latent profile models to find how individuals with GI symptoms cluster when considering both GI and psychological symptoms versus GI symptoms alone.
- Results showed a high degree of similarity in clustering, suggesting that incorporating psychological traits into DGBI classification could lead to more accurate and nuanced categorization of individuals with these disorders.
Background: This SRMA reviewed and assessed the changes in the severity of disorders of gut-brain interaction (DGBI) symptoms during the COVID-19 pandemic, and evaluated factors associated with symptom severity changes.
Methods: Electronic databases were searched until February 2024, for articles reporting on changes in symptom severity in DGBI patients during the COVID-19 pandemic. The proportion of DGBI patients who reported a change in their symptom severity were pooled using a random-effects model, and subgroup analyses were conducted to assess the effect of socio-cultural modifiers on symptom severity in DGBI.