Publications by authors named "N Kitaichi"

Article Synopsis
  • Angiopoietin 2 (Ang2) is released in response to VEGFA and is linked to increased inflammation in ocular autoimmune conditions like uveitis.
  • A study measured levels of Ang2 and VEGFA in patients with uveitis and in a mouse model, finding higher levels in those with the condition.
  • The results suggest that targeting both Ang2 and VEGFA might be an effective new treatment strategy for uveitis, as inhibiting them together showed better outcomes than targeting them individually.
View Article and Find Full Text PDF

Background: Tubulointerstitial nephritis and uveitis (TINU) syndrome is an uveits characterized by complications of idiopathic acute tubulointerstitial nephritis, and most cases present only anterior uveitis. We report a case of TINU syndrome in which the presence of choroiditis was revealed by multimodal imaging.

Case Presentation: A 12-year-old male visited our hospital with a 6-day history of ocular pain and hyperemia.

View Article and Find Full Text PDF

Background: Vaccination against the worldwide pandemic coronavirus disease 2019 (COVID-19) is underway; however, some cases of new onset uveitis after vaccination have been reported. We report a case of bilateral acute posterior multifocal placoid pigment epitheliopathy-like (AMPPE-like) panuveitis after COVID-19 vaccination in which the patient's pathological condition was evaluated using multimodal imaging.

Case Presentation: A 31-year-old woman experienced bilateral hyperemia and blurred vision starting 6 days after her second inoculation of the COVID-19 vaccination.

View Article and Find Full Text PDF

Background: Intraocular lymphoma (IOL) is a masquerade syndrome that mimics uveitis, making diagnosis difficult. The serum soluble interleukin-2 receptor (sIL-2R), which is cleaved by matrix metalloproteinase (MMP) -2 and MMP-9, has been recognized as a tumor-related biomarker of malignant lymphomas. The aim of this study was to review the reliability of serum and vitreous sIL-2R for distinguishing IOL from uveitis.

View Article and Find Full Text PDF