Publications by authors named "N Kime"

The Healthy Ageing Challenge aims for people to enjoy at least five extra healthy, independent years of life by 2035, while narrowing the gap between the experiences of the richest and poorest [...

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Background: Female sex is a significant risk factor for pulmonary arterial hypertension (PAH), yet males with PAH have worse survival - a phenomenon referred to as the "sex paradox" in PAH.

Methods: All adult PAH patients in the Pulmonary Hypertension Association Registry (PHAR) with congruent sex and gender were included. Baseline differences in demographics, hemodynamics, functional parameters, and quality of life were assessed by sex.

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Type 1 diabetes (T1DM) is a public health issue for children, young people, and families (CYPF) and requires innovative interventions. The DigiBete app is a self-management and educational app to help CYPF and healthcare professionals (HCPs) manage T1DM, featuring educational advice and resources such as guidance, quizzes, and educational and instructional videos on how to manage T1DM. To assess the impact and implementation of the app, the service-level evaluation deployed a mixed-methods design.

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Pulmonary arterial hypertension (PAH) is a heterogeneous disease within a complex diagnostic and treatment environment. Other complex heart and lung diseases have substantial regional variation in characteristics and outcomes; however, this has not been previously described in PAH. To identify baseline differences between U.

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Article Synopsis
  • The study aimed to assess the feasibility of a clinical trial evaluating two outpatient treatments for mild pulmonary exacerbations (PEx) in children with cystic fibrosis (CF).
  • Participants aged 6-18 were randomly assigned to receive either immediate oral antibiotics or tailored therapy, which emphasized increased airway clearance and only added antibiotics under specific conditions.
  • Results showed that 70% of those in the tailored therapy group successfully avoided antibiotics, indicating that this approach may help reduce antibiotic use in managing mild PEx and that conducting such a trial is possible.
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