Publications by authors named "N Keyworth"

A nosocomial outbreak of salmonellosis affected 22 patients and seven staff on 14 wards in two hospitals with shared catering facilities. The outbreak was characterized by a low level intermittent infection with Salmonella enteritidis phage type 4 over a 19-day period. The epidemiology did not suggest a common source for the outbreak and there was little evidence for person-to-person spread.

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Coagulase-negative staphylococci (C-NS) are a frequent cause of bacteraemia in premature neonates. It is likely that the strains of C-NS causing bacterial sepsis in premature neonates have their origin on the patient's skin surface. We have studied the quantitative development of the skin microflora at eight sites on premature neonates.

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We describe a comparison of the scrub-wash method of Williamson and Kligman and a swab-wash method for the enumeration of cutaneous microflora. The swab-wash method provides a less traumatic alternative to the scrub-wash method and can be used to sample the cutaneous microflora of premature neonates.

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Two hundred and one strains of Staphylococcus aureus isolated from in-patients and out-patients were examined for sensitivity to antibiotics, heavy-metal ions and ethidium bromide and for phage-typing pattern. Heavy-metal ion resistance was less frequent than reported in previous studies and was as frequent in penicillinase non-producing as producing strains. 'Methicillin-resistant' strains were resistance to ethidium bromide and mercury.

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In December 1985 a neonate was transferred to a Yorkshire Regional Neonatology Unit (RNU) from a neighbouring hospital and was subsequently found to be colonized with a 'methicillin-resistant' strain of Staphylococcus aureus (MRSA). Spread of the MRSA was controlled by routine cross-infection methods. The RNU was not closed to new admissions, the economic cost of control measures was small and no neonatal death was attributable to MRSA infection.

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