Publications by authors named "N Kc"

Article Synopsis
  • Weil's disease is a serious form of leptospirosis that can lead to high mortality, with symptoms ranging from mild febrile illness to severe multiorgan failure.
  • A case study of a young immigrant showed symptoms like abdominal pain, vomiting, and body aches, along with issues like elevated bilirubin levels and acute kidney injury.
  • Despite initial tests being negative, the patient's symptoms and travel history indicated leptospirosis, confirmed by a positive IgM test, highlighting the importance of considering rare infections in diagnosis.
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  • Seizures are the most common emergency for kids and this study looks at kids in Eastern Nepal who had their first seizure.
  • The study included 170 children, mostly boys, and most of them were younger than 5 years old, with fever being the most common symptom when they had seizures.
  • The main causes of these seizures were febrile seizures (from fever), neurocysticercosis (a type of infection), and meningitis, and doctors used different tests to figure out what's causing the seizures.
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Article Synopsis
  • Gaur, a vulnerable species, faces population declines due to human pressures, making it crucial to understand their habitat relationships for effective conservation planning in Chitwan National Park, Nepal.
  • The study used line transects to identify Gaur presence and analyzed ecological and human-related factors affecting their habitat use while ranking conservation threats.
  • Findings showed Gaur thrive in areas with dense canopy cover and fewer predators, while key threats included fire, invasive species, human disturbance, and climate change; suggested conservation actions aim to improve habitat management and assess future sustainability.
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Background: Plasmodium falciparum parasitaemia during pregnancy causes maternal, fetal, and infant mortality. Poor pregnancy outcomes are related to blood-stage parasite sequestration and the ensuing inflammatory response in the placenta, which decreases over successive pregnancies. A radiation-attenuated, non-replicating, whole-organism vaccine based on P falciparum sporozoites (PfSPZ Vaccine) has shown efficacy at preventing infection in African adults.

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Neurological damage is the pathological substrate of permanent disability in various neurodegenerative disorders. Early detection of this damage, including its identification and quantification, is critical to preventing the disease's progression in the brain. Tau, glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL), as brain protein biomarkers, have the potential to improve diagnostic accuracy, disease monitoring, prognostic assessment, and treatment efficacy.

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