Publications by authors named "N Kayal"
Article Synopsis
- The study compares the administration times of daratumumab (DARA) for multiple myeloma, highlighting that the subcutaneous (DARA SC) formulation takes significantly less time (3-5 min) compared to the intravenous (DARA IV) formulation (3-7 hours).
- Data were gathered from electronic health records of patients at Mayo Clinic who received DARA between April 2017 and October 2021, analyzing patient experiences with both administration methods.
- Results showed that DARA SC led to 2.7-3.0 hours shorter clinic times and reduced incidences of administration-related reactions, suggesting efficiency and resource-saving benefits of the subcutaneous method.
Borrelia burgdorferi can affect the nervous system in various ways, which can generate significant confusion and dilemma regarding diagnosis. From India, a country until recently known to be a nonendemic zone for Lyme disease, several cases and one study of Lyme neuroborreliosis have been published. The aim of this study was to describe a young woman with bilateral facial nerve palsy as the presenting manifestation of Lyme neuroborreliosis.
View Article and Find Full Text PDFUnderstanding the relationships between pre-existing conditions and complications of COVID-19 infection is critical to identifying which patients will develop severe disease. Here, we leverage ~1.1 million clinical notes from 1803 hospitalized COVID-19 patients and deep neural network models to characterize associations between 21 pre-existing conditions and the development of 20 complications (e.
View Article and Find Full Text PDFBackground: As the coronavirus disease 2019 (COVID-19) vaccination campaign unfolds, it is important to continuously assess the real-world safety of Food and Drug Administration (FDA)-authorized vaccines. Curation of large-scale electronic health records (EHRs) enables near-real-time safety evaluations that were not previously possible.
Methods: In this retrospective study, we deployed deep neural networks over a large EHR system to automatically curate the adverse effects mentioned by physicians in over 1.
Background: Consecutive negative SARS-CoV-2 PCR test results are being considered to estimate viral clearance in COVID-19 patients. However, there are anecdotal reports of hospitalization from protracted COVID-19 complications despite such confirmed viral clearance, presenting a clinical conundrum.
Methods: We conducted a retrospective analysis of 222 hospitalized COVID-19 patients to compare those that were readmitted post-viral clearance ( = 49) with those that were not re-admitted post-viral clearance ( = 173) between February and October 2020.