Publications by authors named "N Kashyap"
Invasive fungal diseases are an important public health concern due to an increase in the at-risk population and high mortality associated with these infections. Managing invasive fungal infections poses a significant challenge given the limited antifungal options and the emergence of resistance in key fungal pathogens. Through a comprehensive approach, we evaluated the in vitro antifungal activity and the in vivo efficacy of two novel lipopeptides, AF and AF in murine models of disseminated candidiasis, cryptococcosis, and aspergillosis.
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- - The Foot Function Index (FFI) is a standardized tool assessing the effects of foot problems on daily activities, and a Hindi version (FFI-Hi) was developed to address the needs of the 571 million Hindi speakers worldwide facing foot issues.
- - The study involved translating and adapting the FFI into Hindi, followed by testing its reliability and validity with 223 participants, primarily males with an average age of 47, most suffering from plantar fasciopathy.
- - The results showed that the FFI-Hi has good internal consistency and excellent reproducibility, making it a reliable tool for clinical and research purposes in Hindi-speaking populations.
Background: Overnight sleep promotes memory consolidation, although few studies report no effect of sleep on memory. Previous studies suggest significant correlation between sleep dependent memory consolidation and spindle density. The present study is an attempt to understand the effects of sleep on false memories expressed as function of spindle density.
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- The study investigates the role of solute carrier family transporters (SLCs) in the placenta, linking their dysregulation to pregnancy disorders like preeclampsia (PE) and intrauterine growth restriction (IUGR).
- Researchers conducted a meta-analysis of public data and verified findings through qPCR, focusing on differentially expressed SLCs in PE and IUGR samples.
- The results showed significant downregulation of specific SLCs (SLC6A8, SLC16A10, SLC25A3, SLC29A3) in affected placental samples, suggesting their potential role in the pathogenesis of these pregnancy complications.
Background: Treatment of alcohol withdrawal syndrome (AWS) in hospitals is inconsistent. Electronic health record (EHR) order sets protocolize care.
Objective: We examined variation in AWS order sets across hospital organizations and their concordance with AWS guidelines.