[Evaluation of the Functional Reserve and Exercise Tolerance in Patients with CHF in Clinical Trials (Consent Document of the Editorial board of the Journal of Cardiology, the Board of the Society of Specialists in Heart Failure (SSHF) and Working Group "Non-drug treatment methods" of SSHF)].

Assessing the functional capacity and exercise tolerance is an important and widely used research tool in patients with heart failure. It is used not only in cardiac rehabilitation and physical therapy, but also for inclusion criteria and outcome measures in studies of drug interventions. This document outlines the scope, guidelines for the implementation and interpretation, and limitations of the methods for assessing the functional capacity and exercise tolerance in clinical trials in patients with heart failure.

[Possibilities of Predicting Peak Oxygen Consumption in Patients With Chronic Heart Failure According to the 6‑Minute Walk Test].

Aim: To determine the correlation between the results of the 6-minute walk test (6MWT) and peak oxygen consumption (VO2peak) for populations of patients with chronic heart failure with pronounced clinical and demographic differences; to study a possibility of indirect measurement of VO2peak based on the results of 6MWT using the formulas available from the literature.

Material And Methods: Two databases were analyzed: 50 patients included in the AEROFIT study (group A), and 31 patients from the Almazov National Medical Research Center (group B). The inclusion criteria were the availability of data from the cardiopulmonary stress test and the 6MWT.

[Red cell distribution width as a predictor of impaired exercise capacity in patients with heart failure].

Aim    To test a hypothesis that increased values of red cell distribution width (RDW) in patients with chronic heart failure (CHF) can be related with low exercise tolerance.Material and methods    102 patients were evaluated who had CHF with mid-range and reduced left ventricular ejection fraction (LV EF) without anemia (72% men, mean age 66±10.2 years).

ASSOCIATION OF IL-10 AND RESISTIN IN APPARENTLY HEALTHY ELDERLY POPULATION.

There is a growing body of evidence suggesting that the elderly population is characterized by chronic low-grade inflammation ("inflammaging"). Age associated inflammation can be caused by a decrease in the level of IL-10, one of the anti-inflammatory cytokines during aging. The binding of IL-10 to adipose tissue is very important.

MINERAL WATER "DZUGURI" AND TYPE 2 DIABETES MELLITUS: SCREENING RESULTS.

Diabetes Mellitus (DM) is one of the major public health issues worldwide causing a heavy burden on health systems and economies of many countries. In this regard, it is crucial to develop and implement low-cost interventions aimed to early prevention and effective management of DM (particularly T2DM). Various studies worldwide indicated positive effect of natural mineral waters on regulating blood glucose level.