Publications by authors named "N Kadowaki"
Cytokeratin-positive interstitial reticulum cell (CIRC) tumor is an extremely rare malignant neoplasm and a subtype of fibroblastic reticular cell tumor, classified within the dendritic cell tumor group. We describe a case of an epicardial CIRC tumor that was resected and subsequently recurred in the left pulmonary hilum. This recurrence was treated with immunotherapy followed by radiotherapy.
View Article and Find Full Text PDFBackground: Despite the autoimmune nature of psoriasis, the potential association between psoriasis and interstitial lung disease (ILD) remains underexplored. This study aimed to investigate the frequency and clinical features of ILD in patients with psoriasis and propose a new conceptual framework of "ILD associated with psoriasis".
Methods: A retrospective analysis of 117 patients with psoriasis was conducted, excluding those without chest imaging prior to methotrexate or biologic use and those with other comorbidities leading to ILD.
Arthritis is one of the most common symptoms of Behcet's Disease (BD) observed in 57% of Japanese patients with BD. The relationship between arthritis and other clinical symptoms of BD and the impact of arthritis on the quality of life (QOL) of patients with BD are still unclear. Therefore, the current study aimed to clarify the differences in clinical symptoms depending on the presence or absence of arthritis and evaluate the impact of arthritis on QOL in these patients.
View Article and Find Full Text PDFBackground: Lung cancer was often diagnosed by malignant pleural effusion (MPE). Excessive MPE is generally discarded. The establishment of cell lines and the generation of cancer mouse models have the potential to be directly linked to personalized medicine.
View Article and Find Full Text PDFArticle Synopsis
- Tumor flare reaction (TFR) is an increase in tumor size during immune therapy that may be mistaken for disease progression, usually indicating inflammation rather than actual worsening of the disease.
- A case study involves a 62-year-old man with aggressive lymphoma who experienced TFR after starting treatment with epcoritamab, leading to swollen lesions that were treated with dexamethasone.
- The examination of a skin biopsy confirmed the presence of specific immune cells, highlighting that TFR could signify a positive tumor response to epcoritamab, suggesting that it's important to recognize and understand TFR for effective treatment planning.