Can hyperoxic stress cause susceptibility to acute seizure in the neonatal period?: a rat study.

Preterm neonates encounter hyperoxia relatively early, and are more exposed to hyperoxic stress due to their insufficient antioxidant defense mechanisms. This study was planned around the hypothesis that this hyperoxic effect may cause a disposition to future acute seizures. This study was composed of two main groups Hyperoxy and Control (Room air with normal O levels) Groups.

Risk factors affecting seizure recurrence in childhood epilepsy during short-term follow-up.

Purpose: The aim of this study is to examine the factors affecting seizure recurrence in pediatric patients diagnosed with epilepsy.

Methods: Three hundred patients presenting to the pediatric neurology clinic between 2015 and 2018 and diagnosed with epilepsy and treated with single antiseizure drug were included in the study. Medical histories and clinical and laboratory findings were retrieved retrospectively from the hospital data system.

Plasma levels of vasoactive neuropeptides in pediatric patients with migraine during attack and attack-free periods.

Background: Increasing evidence suggests that vasoactive neuropeptides such as pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38), substance P, calcitonin gene-related peptide, and vasoactive intestinal peptide are involved in the pathophysiology of migraine in adults, but their role in pediatric migraineurs remains unclear. We prospectively investigated plasma levels of these vasoactive neuropeptides in pediatric migraine patients without aura and compared the results with those of age-matched healthy controls.

Methods: Thirty-eight children aged 6-18 years with migraine without aura and 20 age-matched control subjects were included in the study.

Epilepsy and drug-resistant epilepsy in children with cerebral palsy: A retrospective observational study.

Purpose: The objective of this study was to determine risk factors for epilepsy and drug-resistant epilepsy (DRE) development in children with cerebral palsy.

Method: Two hundred twenty-nine patients presenting to the pediatric neurology clinic and diagnosed as having cerebral palsy between November 2016 and November 2019 were included in the study. Medical histories and clinical, laboratory, and radiological findings were examined retrospectively from patient records in the hospital data system.

The role of clinical signs in the diagnosis of papilledema: development of an algorithm.

Purpose: The aim of this study was not only to emphasize the role of clinical signs as well as ophthalmologic evaluation for accurate and differential diagnosis of papilledema (PE), but also to present an instructive algorithm that would help to eliminate unnecessary examinations and treatments.

Method: The files of 43 patients (ages 0-18) diagnosed with PE were retrospectively reviewed. The study included 25 patients from our pediatric neurology outpatient clinic, who were thought to have PE, and 18 patients, who were referred from the external centers to our hospital with a pre-diagnosis of PE.