Publications by authors named "N K S Sampaio"
Introduction: Long COVID is a recent pathological entity. Its manifestations and impact on health and quality of life and, on a larger scale, at an economic and social level may be very significant, reflecting a challenge for the future. The family doctor plays a major role in the care of these patients and must be aware of this new reality.
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- The study investigates trends in Pediatric Sickle Cell Disease (SCD) in Brazil from 2008 to 2022, focusing on incidence, mortality rates, and healthcare costs associated with the disease.
- It analyzed data from 81,942 hospitalizations, finding that 74.08% were crisis-related, with higher rates in males and children under five, particularly in the Southwest region of Brazil.
- The results indicate a need for targeted interventions to improve early detection and healthcare access, suggesting that addressing these factors can help manage the significant burden of SCD in pediatric populations.
During virus infection, many host proteins are redirected from their normal cellular roles to restrict and terminate infection. Heterogeneous nuclear ribonucleoproteins (hnRNPs) are cellular RNA-binding proteins critical to host nucleic acid homeostasis, but can also be involved in the viral infection process, affecting virus replication, assembly and propagation. It has become evident that hnRNPs play important roles in modulation of host innate immunity, which provides critical initial protection against infection.
View Article and Find Full Text PDFCaregiver burden, hopelessness, and anxiety: Association between sociodemographic and clinical profiles of patients with stroke.
J Stroke Cerebrovasc Dis
November 2024
Objectives: This study aimed to evaluate the association between the sociodemographic characteristics of caregivers and patients with stroke, clinical data on stroke, and disability with caregiver burden, hopelessness, and anxiety.
Materials And Methods: This cross-sectional study included patients with stroke of either sex, aged >18 years. Data were collected between January 2020 and July 2021.
Patients with end-stage heart disease who undergo a heart transplant frequently have simultaneous kidney insufficiency, therefore simultaneous heart and kidney transplantation is an option and it is necessary to understand its characteristics and long-term variables. The recipient characteristics and operative and long-term variables were assessed in a meta-analysis. A total of 781 studies were screened, and 33 were thoroughly reviewed.
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