Emerging lineages A2.2.1 and A2.2.2 of human metapneumovirus (hMPV) in pediatric respiratory infections: Insights from India.

Objectives: Human metapneumovirus (hMPV) is recognized as a significant cause of acute respiratory infections among infants under 5 years of age.

Methods: Nasal swabs collected from January 2021 to June 2024 were screened to detect hMPV using reverse transcription-quantitative polymerase chain reaction. Furthermore, representative positive samples were sequenced and subjected to phylogenetic analysis.

Assessment of Nanosilver Fluoride Application on the Microtensile Bond Strength of Glass Ionomer Cement and Resin-modified Glass Ionomer Cement on Primary Carious Dentin: An Study.

Background And Objectives: Nanosilver sodium fluoride (NSF) has recently gained popularity in dentistry as an alternative to silver diamine fluoride (SDF) due to its drawbacks of staining the tooth black and possibly causing soft tissue injury, which has been eliminated in NSF due to the nanoparticle size of silver. This study aims to assess the microtensile bond strength of glass ionomer cement (GIC) and resin-modified glass ionomer cement (RMGIC) with pretreatment of NSF on extracted primary carious teeth.

Materials And Methods: Teeth were stored in 10% formalin.

Characterizing human respiratory syncytial virus among children admitted with acute respiratory tract infections from 2019 to 2022.

Respiratory syncytial virus is a major causative agent of lower respiratory tract infection in children, especially infants with substantial morbidity and mortality implications. The virus undergoes continuous evolution documented by accumulation of mutations in the glycoprotein gene necessitating vigilant surveillance to provide essential data to epidemiologists and researchers involved in development of vaccines. This study was aimed to perform molecular characterization of respiratory syncytial virus (RSV) among children ≤ 5 years admitted in hospital.

Influence of COVID-19 over seasonal influenza activity in southern India.

Basic epidemiological data is urgently needed in order to ascertain the changes brought about by COVID-19 pandemic, and help researchers, clinicians, and policy makers in addressing these issues. Data on influenza positivity from 2009 to 2019 was collected from Regional Influenza laboratory, JIPMER. Being COVID testing centre we tested samples (2020-2023) from Tamilnadu and Pondicherry.

Defining the key intrahepatic gene networks in HCV infection driven by sex.

Objective: The transcriptional response in the liver during HCV infection is critical for determining clinical outcomes. This issue remains relatively unexplored as tissue access to address this at scale is usually limited. We aimed to profile the transcriptomics of HCV-infected livers to describe the expression networks involved and assess the effect on them of major predictors of clinical outcome such as IFNL4 (interferon lambda 4) host genotype and sex.