[Mechanical corneal injury diagnosis using infrared spectroscopy].

Method for express diagnosis of mechanical corneal injury using infrared spectroscopic analysis of tear fluid is proposed. Differential diagnosis of open and closed corneal injuries in absence of clinical data is presented. Clinical material is provided by patients with open globe injuries--25 patients (25 eyes) and 25 patients (25 eyes) with closed globe injuries.

[Partial reversion of the phenotype of a poorly differentiated hepatocellular carcinoma in a three-dimensional culture].

In vivo, normal tissues and organs have a three-dimensional structure and function in a three-dimensional environment. The standard two-dimensional cell culture conditions drastically differ from those in vivo. For this reason, three-dimensional cultures based on different variants of the extracellular matrix are more adequate for analyzing normal and tumor cell growth.

[Clinical efficacy of jointless therapeutic amnion surfacing of the cornea in its diseases and injury].

The surgical treatment option for corneal diseases and injury - therapeutic silicone-dried amnion surfacing is widely used in ophthalmological care. The Voronezh Regional Clinical Eye Clinic has developed and introduced into a therapeutic process an alternative option, namely jointless therapeutic amnion corneal surfacing, by using a soft contact lens and viscoelastic. This option is easy-to-use and enables psychoemotional stress associated with a surgical intervention to be avoided.

[A simple method of testing the sensitivity to antineoplastic agents on human tumors in vivo].

BRO human melanoma cells, encapsulated in fibrinogen clots and implanted under the subrenal capsule of immunosuppressed mice, serve as a model for evaluating the effects of chemotherapeutic agents on human tumors in vivo. Histological examination of 8-day tumors in mice which had received 4.5 Gy prior to implantation, showed that the cells were largely viable.