[Morphological changes in experimental melanoma B-16 effected by a conjugate of polyvinylpyrrolidone and metal-organic complex of copper and melphalan].

Data on morphological alterations in experimental melanoma B-16 induced by conjugate of polyvinylpyrrolidone and metal-organic complex of copper and melfalon are presented. The antitumor effect of the synthetic conjugate, which inhibits melanoma-16 growth, is adequately tolerated by bone marrow cells. Conjugate accumulation among the dividing cells inhibits the proliferatrive capability of malignant cells and causes other specific morphological changes to occur.

[20 years' experience in the use of local hyperthermia in the treatment of inoperable cancer of the esophagus].

The paper discusses the results of treatment of 280 patients with inoperable esophageal cancer which included local hyperthermia, radiotherapy, hyperglycemia and chemotherapy. 122 patients receiving radiotherapy alone served as controls. The complete remission rate obtained with local hyperthermia and radiotherapy was 2.

[The immediate results of the combined treatment of stage-III breast cancer].

Immediate results of complex treatment were studied in 185 patients with stage IIIa, b (T1-2N2M0 and T3N0-2M0) nodular breast cancer. Preoperative chemoradiation treatment incorporated microwave procedure. All patients had been radically mastectomized after Patey.