Herpes Simplex Virus Encephalitis in a Post-operative Case of Follicular Thyroid Carcinoma.

Herpes simplex virus (HSV) encephalitis is a life-threatening consequence of HSV infection of the central nervous system. Early antiviral therapy is most effective, necessitating prompt diagnosis. We report a case of atypical HSV encephalitis.

Discovery of small molecules against porcine reproductive and respiratory syndrome virus replication by targeting NendoU activity.

Unlabelled: Porcine reproductive and respiratory syndrome (PRRS) remains a major threat to animal health and causes substantial economic losses worldwide. The nonstructural protein 11 (NSP11) of the causative agent, PRRS virus (PRRSV), contains a highly conserved nidoviral uridylate-specific endoribonuclease (NendoU) domain essential for viral replication and immune evasion. Targeting NSP11 offers a novel approach to antiviral intervention.

Timing of Therapeutic Extractions Can Affect En Masse Anterior Retraction: A Split Mouth Randomized Clinical Trial.

Objective: To investigate the effect of deferred timing of therapeutic extraction on the rate of space closure during en masse anterior retraction.

Methods: Twenty-six patients (aged 16-24 years) with bimaxillary protrusion, crowding <3 mm, requiring bilateral extraction of four first premolars were recruited. Permuted block randomization was done.

Phage-Encoded Virulence Factor, Gp05, Alters Membrane Phospholipids and Reduces Antimicrobial Susceptibility in Methicillin-Resistant Staphylococcus aureus.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen causing severe endovascular infections. The prophage-encoded protein Gp05 has been identified as a critical virulence factor that contributes to MRSA persistence during vancomycin (VAN) treatment in an experimental endocarditis model. However, the underlining mechanisms driving this persistence phenotype remain poorly understood.

Dosimetric Evaluation of Different Algorithms on Heterogeneous Slab Phantom Using CMS XiO and MONACO Treatment Planning System for 4MV, 6MV and 15MV Beam Energy: An Institutional Study.

Aim: To study the dosimetric behavior of dose computational algorithms in inhomogeneous medium using CMS XiO and MONACO treatment planning system (TPS) for 4 megavoltage (MV), 6 MV and 15 MV photon beam energies.

Material And Methods: Styrofoam blocks of thickness 1.90 cm, 3.