Publications by authors named "N K Metzger"
Article Synopsis
- The hormone ghrelin plays a protective role in cancer-related anorexia-cachexia syndrome (CACS), with its levels rising to help combat weight loss and anorexia in cancer patients.
- A study found that deleting ghrelin worsened body weight and fat loss in mice with cancer, while deleting LEAP2, a ghrelin antagonist, seemed to lessen the severity of CACS.
- In human patients with CACS, a lower ratio of plasma LEAP2 to total ghrelin was associated with better weight stability, indicating a possible protective mechanism against worsening CACS.
Background: While successful information transfer and seamless medication supply are fundamental to medication safety during hospital-to-home transitions, disruptions are frequently reported. In Germany, new legal requirements came into force in 2017, strengthening medication lists and discharge summaries as preferred means of information transfer. In addition to previous regulations - such as dispensing medication at discharge by hospital pharmacies - hospital physicians were now allowed to issue discharge prescriptions to be supplied by community pharmacies.
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