[The detoxifying and immunocorrective properties of some sorption treatment methods in suppurative-septic poisoning in experimental diffuse peritonitis].

During septic intoxication in diffuse peritonitis poisoning is accompanied by circulatory and volemic failures, considerable changes in immune status, basically of the cellular component of T-system. Several sorption methods were applied which produced different effects on the pathologic process. Extracorporeal application of spleen-xeno and ultraviolet irradiation of autoblood considerably increased the immune reactivity.

[Immunocorrection in destructive pancreatitis].

An immunocorrective effect of current methods of detoxication in experimental acute destructive pancreatitis was studied on 40 mongrel male dogs with body mass 13-15 kg. It was found that destructive pancreatitis is associated with a decrease in immunological reactivity, mainly in T-cell immunity component. Application of spleen xeno and ultraviolet irradiation of autoblood proved most effective as early treatment.

[Extracorporeal methods for detoxification in the combined treatment of gunshot peritonitis].

On the basis of examination results and treatment of 49 patients with abdominal gunshot injuries the article emphasizes that the clinical picture of gunshot peritonitis develops much faster, and the syndrome of intoxication proceeds far harder, than in cases of peritonitis with another etiology. The authors make a conclusion that an early application of extracorporal methods of detoxication (hemosorption, plasmapheresis, ultraviolet irradiation of autologous blood, xenospleen connection) could minimize the level of intoxication and contribute to the correction of the immune status.

[The choice of an adequate method for detoxification and immunocorrection in destructive experimental pancreatitis].

Thus, basing on the data obtained it was stated that the destructive pancreatitis is always accompanied by intoxication. A certain weakening of the immune mechanisms took place, mainly of its T-cellular chain. Detox methods of treatment had different effects on the organism.

[The role of hemosorption in preventing and treating pulmonary disorders in patients with peritonitis and acute intestinal obstruction].

An analysis of treatment and examination of 80 patients with peritonitis and acute intestinal obstruction of different etiology has been made when hemosorption was used for struggle against intoxication. It has been shown that hemosorption possessing a potent detoxicating effect considerably facilitates activation of the non-gas-exchange functions of the lungs. However, losses of the surfactant synthesis components during hemocarboperfusion as well as absorption of oxygen by certain sorts of charcoal (SKN-4M, SKN-1K) results in arterial hypoxemia.