Publications by authors named "N K JENSEN"
Context: Gestational diabetes mellitus (GDM) increases the risk of future type 2 diabetes (T2DM), but effective and feasible interventions to reduce this risk are lacking.
Objective: To evaluate the effectiveness of a family-based health promotion intervention on T2DM risk factors and quality of life among women with recent GDM.
Design: Multicenter, parallel, open-label randomized controlled trial with 2:1 allocation ratio.
Fungi provide valuable solutions for diverse biotechnological applications, such as enzymes in the food industry, bioactive metabolites for healthcare, and biocontrol organisms in agriculture. Current workflows for identifying new biocontrol fungi often rely on subjective visual observations of strains' performance in microbe-microbe interaction studies, making the process time-consuming and difficult to reproduce. To overcome these challenges, we developed an AI-automated image classification approach using machine learning algorithm based on deep neural network.
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- The MJF-14 PLA is a new technique for detecting α-synuclein aggregates, demonstrating high specificity and sensitivity for non-Lewy body pathology.
- This assay shows a strong correlation between α-synuclein aggregation and specific conditions in both cell cultures and human neuronal samples linked to neurodegenerative diseases.
- The findings indicate that a significant amount of α-synuclein pathology occurs before the formation of Lewy bodies in diseases such as Parkinson's, suggesting the need for further research using brain samples.
Assays for quantifying aggregated and phosphorylated (S129) human α-synuclein protein are widely used to evaluate pathological burden in patients suffering from synucleinopathy disorders. Many of these assays, however, do not cross-react with mouse α-synuclein or exhibit poor sensitivity for this target, which is problematic considering the preponderance of mouse models at the forefront of pre-clinical α-synuclein research. In this project, we addressed this unmet need by reformulating two existing AlphaLISA SureFire Ultra™ total and pS129 α-synuclein assay kits to yield robust and ultrasensitive (LLoQ ≤ 0.
View Article and Find Full Text PDFBackground: Mental health disease constitutes 25% of the total burden of disease in Denmark. In the last few years, an increasing tendency for seeking the ocean has arisen, and winter bathing is one of the outdoor activities with a large rise in popularity.
Objectives: The purpose of this study was to explore if and how regular winter bathing in blue spaces can affect people's mental health.