In Situ Metal Vacancy Filling in Stable Pd-Sn Intermetallic Catalyst for Enhanced CC Bond Cleavage in Ethanol Oxidation.

A common challenge in electrochemical processes is developing high performance, stable catalysts for specific chemical reactions. In this work, a Pd-Sn intermetallic compound with   Pd site deficiency (PdSn) (x = 0.06) and trace amount of SnO was synthesised by controlled process.

Neo-aortic valve replacement in arterial switch operation in a 9-year-old child.

The surgical management of d-transposition of the great arteries (dTGA), ventricular septal defect (VSD), and left ventricular outflow tract obstruction (LVOTO) poses intricate challenges, demanding tailored surgical interventions. This case report elucidates a patient involving a 9-year-old child with dTGA, VSD, and LVOTO with a dysplastic pulmonary valve with adequate annulus who underwent neo-aortic valve replacement with a mechanical prosthesis, arterial switch, and VSD closure. The recovery of the patient was uneventful and follow-up echocardiogram and clinical evaluation at 18 months have remained satisfactory.

A controlled co-assembly approach to tune temperature responsiveness of biomimetic proteins.

The controlled co-assembly of biomacromolecules through tuneable interactions offers a simple and fascinating opportunity to assemble multiple molecules into a single entity with enhanced complexity and unique properties. Herein, our study presents a dynamic co-assembled system using the multistimuli responsive intrinsically disordered protein Rec1-resilin and the adhesive hydrophilic protein silk sericin (SS). We utilized advanced characterization techniques including circular dichroism (CD) spectroscopy, dynamic light scattering (DLS), small-angle X-ray scattering (SAXS), and small/ultra-small angle neutron scattering (SANS/USANS) to elucidate the detailed co-assembly behavior of the system and its evolution over time and temperature.

The oligonucleotides containing N7-regioisomer of guanosine: influence on thermodynamic properties and structure of RNA duplexes.

During the chemical synthesis of the purine riboside, N7-regioisomer is kinetically formed, whereas N9-regioisomer is a thermodynamically formed product. We have studied the effect of substituting N9-regioisomer of guanosine with its N7-regioisomer (N7-guanosine, 7G) at a central position of several RNA duplexes. We found that this single substitution by 7G severely diminished their thermodynamic stabilities when 7G paired with C and U, but remarkably, led to a significant amount of stabilization in most of the duplexes when forming mismatches with G and A.