Publications by authors named "N K Cappella"

Background: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are highly prevalent but underdiagnosed.

Aims: We used an electronic health record data network to test a population-level risk stratification strategy using noninvasive tests (NITs) of liver fibrosis.

Methods: Data were obtained from PCORnet sites in the East, Midwest, Southwest, and Southeast United States from patients aged [Formula: see text] 18 with or without ICD-10-CM diagnosis codes for NAFLD, NASH, and NASH-cirrhosis between 9/1/2017 and 8/31/2020.

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Rehabilitation research focuses on determining the components of a treatment intervention, the mechanism of how these components lead to recovery and rehabilitation, and ultimately the optimal intervention strategies to maximize patients' physical, psychologic, and social functioning. Traditional randomized clinical trials that study and establish new interventions face challenges, such as high cost and time commitment. Observational studies that use existing clinical data to observe the effect of an intervention have shown several advantages over RCTs.

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Objective: As a long-standing Clinical and Translational Science Awards (CTSA) Program hub, the University of Pittsburgh and the University of Pittsburgh Medical Center (UPMC) developed and implemented a modern research data warehouse (RDW) to efficiently provision electronic patient data for clinical and translational research.

Materials And Methods: We designed and implemented an RDW named Neptune to serve the specific needs of our CTSA. Neptune uses an atomic design where data are stored at a high level of granularity as represented in source systems.

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Article Synopsis
  • There is increased interest in utilizing electronic health records (EHRs) to recruit research participants, but few studies detail the practical methods or compare electronic and in-person recruitment approaches across different health systems.
  • The study aimed to outline the recruitment process steps, efficiency of various recruitment strategies, and the characteristics of the participants recruited.
  • Results indicated a total of 5,051,187 eligible patients, with in-person recruitment being the most efficient (33.5%), while electronic messaging showed lower efficiency (2.9%), but successfully enrolled a higher proportion of Black patients compared to other methods.*
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Introduction: To improve the management of overweight and obesity in the primary care setting, an analysis of patient perceptions of weight status and predictors of weight loss attempts for those with overweight and obesity is needed.

Methods: Primary care patients (n=949) across 5 health systems in the Mid-Atlantic region of the U.S.

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