Publications by authors named "N K C Lau"

Background: Singapore's large aging population poses significant challenges for the health care system in managing cognitive decline, underscoring the importance of identifying and implementing effective interventions. Cognitive training delivered remotely as a digital therapeutic (DTx) may serve as a scalable and accessible approach to overcoming these challenges. While previous studies indicate the potential of cognitive training as a promising solution for managing cognitive decline, understanding the attitudes and experiences of older adults toward using such DTx platforms remains relatively unexplored.

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Objectives: To assess the incidence and clinical findings associated with the presence of ammonium urate urolithiasis in dogs with congenital portosystemic shunts.

Materials And Methods: A retrospective review of dogs diagnosed with extrahepatic portosystemic shunts or intrahepatic portosystemic shunts in 15 referral hospitals between 2010 and 2023. Data including signalment, clinical signs, physical examination findings and clinicopathologic test results at the time of the diagnosis were collected, and the presence of ammonium urate urolithiasis was recorded.

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  • The study compares scene-independent and scene-dependent eye metrics to evaluate how well they assess performance in simulated psychomotor tasks for trainees.
  • Scene-dependent metrics showed a stronger correlation with performance levels compared to scene-independent metrics, based on the analysis of eye-tracking and task completion data.
  • The results suggest that using scene-dependent eye metrics could improve skill assessment and training, ultimately enhancing the competency of operators in various fields like surgery and aviation.
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Recent advances in machine perfusion have revolutionised the field of transplantation by prolonging preservation, permitting evaluation of viability prior to implant and rescue of discarded organs. Long-term perfusion for days-to-weeks provides time to modify these organs prior to transplantation. By using long-term normothermic machine perfusion to facilitate liver splitting and subsequent perfusion of both partial organs, possibilities even outside the clinical arena become possible.

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  • The study compares the effectiveness of continuous wound infusion (CWI) of local anesthetic with thoracic epidural analgesia (TEA) for postoperative pain management after pancreaticoduodenectomy (PD).
  • Results showed that while TEA provided better pain relief at rest and while coughing on the second postoperative day, CWI was equally effective for overall pain management across the first five days post-surgery.
  • CWI allowed for quicker recovery milestones, such as faster bowel movements and diet initiation, along with lower rates of analgesic failure and nausea/vomiting compared to TEA.
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